58-33-3

Quality products make an important contribution to long-term revenue and profitability. Top Quality Chinese Factory supply 58-33-3 Promethazine hydrochloride

1.What is the Promethazine hydrochloride ?

PM is used for the treatment of allergic symptoms, often given at night because of its marked sedative effects. Drug hypersensitivity reactions and allergic conditions have also been treated with promethazine especially in emergencies. It can also be used in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections; in fact, inhalation therapy for relieving bronchial spasm is made by quaternary salts of promethazine. PM is sometimes used for its sedative effects and in some countries is marketed for this purpose, including the sedation of young children as nasal sleep introducing drug, or it can be used as an anaesthetic premedication to produce sedation, reduce anxiety, or to reduce postoperative nausea and vomiting as dose-controlled transdermal device. The drug is often given in conjunction with an opiate analgesic such as pethidine, particularly in obstetrics. Taken before travelling, promethazine is effective in preventing motion sickness. Vomiting from other causes can be treated with higher or more frequent doses. Combination of histamine H1R and H4R antagonist is used for the treatment of neoplastic disorders, consisting in a cytotoxic agent as an agent to prevent multidrug resistance[9]. It is also used as a contraceptive killing spermin vagina, since promethazine hydrochloride has strong sperm-killing effect, or as an antimutagenic treatment of bacteria by killing bacteria. Bathing preparation, which contains a histamine H1-antagonist, inhibits the decomposition of hyaluronic acid, playing an important role inmoisture and tension of skin to improve roughened or dried skin. This cosmetic can take such a form as gel, cream, spray, cataplasm, lotion, pack, milky lotion, or powder. It can also be a melanogenesis-suppressing agent useful as a skin-beautifying cosmetic, a skin-aging prevention agent, and so forth, by using a phenothiazine compound having remarkable melanogenesis-suppressing effect. Application of PM can be used for treating haemorrhoids with no pain, no side effect, no operation, and no hospitalization, but low cost[10–12]. Promethazine has been used to control extrapyramidal disorders in children caused by metoclopramide and levodopa-induced dyskinesia in patients with Parkinson’s disease. In young children undergoing dental procedures, it has been suggested that promethazine can be used in conjunction with chloral hydrate to produce sedation, as there was observed a lower incidence of nausea than when chloral hydrate was administered alone. In some countries, promethazine is available as a 2% cream without medical prescription for the treatment of allergic skin conditions, insect bites, and burns.

Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; sedative; anticholinergic; antiserotoninergic; local anesthetic; in the treatment of motion sickness, cough linctuses, nausea, and allergic conditions; used to control Parkinsonian symptoms and as central nervous system depressant; in pills, syrup, injections and suppositories.

2.What is the CAS number for Promethazine hydrochloride ?

The CAS number of Promethazine hydrochloride is 58-33-3.

More information of Promethazine hydrochloride 58-33-3 are:

3.What are another words for Promethazine hydrochloride ?

Synonyms for Promethazine hydrochloride 58-33-3:Phenothiazine, 10-[2-(dimethylamino)propyl]-, monohydrochloride (8CI);10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Anergan 25;Diprazin;Dorme;Fenazil;Genphen;Himazin;Lergigan;Mepergan;NSC 231688;PhanerganD;Phencen;Phenergan;Phenergan VC;Plletia;Promasun;Prorex;Provigan;Pyrethia;Romergan;

4.What is the molecular formula of Promethazine hydrochloride?

The chemical formula of  Promethazine hydrochloride is C17H20N2S.HCl which containing 17 Carbon atoms,21 Hydrogen atoms,2 Nitrogen atoms and 1 Chlorine atoms,and the molecular weight of  Promethazine hydrochloride is 320.886.

5.What is Promethazine hydrochloride (58-33-3) used for?

Promethazine hydrochloride is a first-generation histamine H1 receptor antagonist with antihistamine, antiemetic, central nervous system depressant, sedative, anticholinergic, antiserotoninergic, and local anesthetic properties. It is used in various applications across different industries, including pharmaceutical and healthcare.
Used in Pharmaceutical Industry:
Promethazine hydrochloride is used as an antihistamine for the treatment of allergic disorders, and as an antiemetic for the management of nausea and vomiting. It is also used as a central nervous system depressant, sedative, anticholinergic, and antiserotoninergic agent.
Used in Motion Sickness Treatment:
Promethazine hydrochloride is used as an antiemetic for the treatment of motion sickness, demonstrating antiemetic effects in ferret models of motion sickness or chemotherapy-induced nausea.
Used in Cough Linctuses:
Promethazine hydrochloride is used in cough linctuses to provide relief from cough and cold symptoms.
Used in Parkinsonian Symptom Control:
Promethazine hydrochloride is used to control Parkinsonian symptoms, offering relief from tremors and muscle stiffness.
Used in Various Forms:
Promethazine hydrochloride is available in various forms, including pills, syrup, injections, and suppositories, making it accessible and convenient for patients with different needs and preferences.

InChI:InChI=1/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H/p-1

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6.Buy Promethazine hydrochloride with the best price .

Jinxin Shengda Air Freight Forwarding (Huizhou City) Co., LTD is a quality supplier of Promethazine hydrochloride. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Promethazine hydrochloride 58-33-3.